Schizophrenia: From the brain to peripheral markers - A consensus paper of the WFSBP Task Forse on biological markers
Авторы:
Stober G. BTN-Shachar D Falkai P. Fonteh A.N., Gawlik M., Glenthoj B.Y., Grunblatt E., Jablensky A., Kim Y-K., Kornhuber J., McNeil T.F., Muller N., Oranje B., Saito T., Saoud M., Schmitt A., Schwaetz M., Thome J., Uzbekov M., Durany N., Riederer P.
Издание:
World J Biol Psychiatry
Год издания:
2009
Номер:
Vol. 10, N 2
Страницы:
127-155
Язык:
English
Аннотация:
The phenotypic complexity, together with the multifarious nature of the so-called "schizophrenic psychoses", limits our ability to form a simple and logical biologically based hypothesis for the disease group. Biological markers are defined as biochemical, physiological or anatomical traits that are specific to particular conditions. An important aim of biomarker discovery is the detection of disease correlates that can be used as diagnostic tools. Method. A selective review of the WFSBP Task Force on Biological Markers in schizophrenia is provided from the central nervous system to phenotypes, functional brain systems, chromosomal loci with potential genetic markers. FULL TEXT +