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Zaytseva Y. Gurovich I.Ya. Sarkisyan G. Sarkisyan V.
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European Neuropsychopharmacology
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Comparative analysis of neurocognitive functioning of patients with schizophrenia and schizoaffective disorder experiencing their first psychotic episode was performed within framework of a complex investigation of neurophysiological and neuropsychological parameters of such patients. This investigation showed that in acute condition both patient groups showed generalized cognitive disturbances with a noticeable accent on problems in the right hemisphere in schizoaffective disorder and a more pronounced left-hemisphere dysfunction in schizophrenia. Along with changes in the clinical picture, specifically, with
reduction of psychopathological phenomena, the patients with schizoaffective disorders also showed positive changes with better chances for
recovery of both basic and variable symptoms while in schizophrenia the cognitive dysfunction was more outlined and less prone to improvement.
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