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Design and validation of standardized clinical and functional remission criteria in schizophrenia

Авторы:

Mosolov S.N. Potapov A.V. Ushakov U.V. Shafarenko A.A., Kostyukova A.B.

Издание:

Neuropsychiatric Disease and Treatment

Год издания:

2014

Номер:

Vol. 10

Страницы:

167-181

Язык:

English

Аннотация:

International Remission Criteria (IRC) for schizophrenia were developed recently by a group of internationally known experts. The IRC detect only 10%–30% of cases and do not cover the diversity of forms and social functioning. Our aim was to design a more applicable tool and validate its use – the Standardized Clinical and Functional Remission Criteria (SCFRC). Methods: We used a 6-month follow-up study of 203 outpatients from two Moscow centers and another further sample of stable patients from a 1-year controlled trial of atypical versus typical medication. Diagnosis was confirmed by International Classification of Diseases Version 10 (ICD10) criteria and the Mini-International Neuropsychiatric Interview (MINI).Conclusion: In schizophrenia outpatients, a greater proportion of stable cases is detected in remission by SCFRC in comparison with IRC. The SCFRC were more sensitive to the full spectrum of schizophrenia. ... FULL TEXT +

Добавил:

Администратор И.М.В. 2014-04-29

Ключевые слова:

schizophrenia, schizoaffective disorder, remission criteria, PANSS, long-acting risperidone

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