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Mnatsakanian E.V. Sharaev M.G. Kryukov V.V. Antipova O.S., Krasnov V.N.
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Objectives: Patients with major depressive disorder (MDD) show
attention bias to the negative emotional stimuli. We aimed at study-
ing the EEG-correlates of unconscious expectation of angry human
faces in MDD patients compared to healthy controls.
Methods: 128-channel EEG was recorded in MDD (23 female and 7
male) and in healthy volunteers (22 female and 8 male) while they
categorized pictures as humans or animals. Half of the pictures were
neutral and half were showing the faces of angry humans or animals.
The pictures were preceded by cues (one for each category), which
meaning was not explained to the participants. We performed the
wavelet analysis of EEG recorded during the face expectation period:
1–2 ms from the cue onset.
Results: We found the emotional modulation (EM) in EEG rhythms
during the expectation of angry vs. neutral faces in both groups.
Statistical comparison of the spectral power using 2 ? 2 factorial
design showed that the EM differences (p < .05
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