Uzbekov M.G. Shikhov S.

BioMedical

2019

Vol. 13, N 3

1/2-2/2

English

Ciliary neurotrophuc factor (CNTF) is a 22-kDA cytokine belonging to the interleukin-6 family and is mainly expressed in glial cells of the central and peripheral nervous systems. Ciliary neurotrophic factor is a neurotrophin which could act as a neuroprotective agent. CNTF plays an important role in the regulation of neuronal development, neuroprotection and may also influence cognitive processes. However, the physiological relevance of circulating CNTF still needs to establish. Depression is one of the most prevalent mental disorders and one of the main causes of disability worldwide. Depression now is a very complicated medical and social problem that in the next years will be only exacerbate.

Администратор КМЕА 2020-05-29

neurotrophuc factor, CNTF, interleukin-6, glial cells, depression

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