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Brancatia G.E. Vieta E. Azorind J. Angste J., Bowdenf C.L., Mosolov S., Youngh A.H., Perugia G.
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Journal of Psychiatric Research
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Background: DSM-5 and ICD-11 define mixed depression as the presence of non-overlapping symptoms of opposite polarity during a major depressive episode. However, such a definition has generated controversy. Methods: 2720 patients with major depression, enrolled in BRIDGE–II–MIX cross-sectional study, were subdivided in clusters using a k-medoids algorithm basedon 32 clinical features.
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