Patterns of response to antidepressants in major depressive disorder: Drug resistance or worsening of depression are associated with a bipolar diathesis

Patterns of response to antidepressants in major depressive disorder: Drug resistance or worsening of depression are associated with a bipolar diathesis

Авторы:

Perugi G. Pacchiarotti I. Cecilia M. Verdolini N., Menculini G., Barbuti M., Angst J., Azorin J.M., Bowden C., Mosolov S., Young A.H., Vieta H.

Издание:

European Neuropsychopharmacology

Год издания:

2019

Номер:

Vol. 29, N 7

Страницы:

825-834

Язык:

English

Аннотация:

Resistance and worsening of depression in response to antidepressants (ADs) are major clinical challenges. In a large international sample of patients with major depressive disorder (MDD), we aim to explore the possible associations between different patterns of response to ADs and bipolarity. A total of 2811 individuals with a major depressive episode (MDE) were enrolled in the BRIDGE-II-MIX study.

Добавил:

Администратор КМЕА 2020-06-03

Ключевые слова:

major depressive disoder, mixed features, antidepressants, resistance to treatment,

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